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1

Reply to "Precision medicine in the clouds"

Magis, Andrew T, Earls, John C, Glusman, Gustavo, Omenn, Gilbert S, Lovejoy, Jennifer C, Price, Nathan D, Hood, Leroy

Journal:

Nature Biotechnology

Year:

2018

Language:

english

File:

PDF, 142 KB

english, 2018

2

P4 medicine: how systems medicine will transform the healthcare sector and society

Flores, Mauricio, Glusman, Gustavo, Brogaard, Kristin, Price, Nathan D, Hood, Leroy

Journal:

Personalized Medicine

Year:

2013

Language:

english

File:

PDF, 807 KB

english, 2013

3

Personalized nutrition through big data

McDonald, Daniel, Glusman, Gustavo, Price, Nathan D

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 268 KB

english, 2016

4

Predictive Big Data Analytics: A Study of Parkinson’s Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations

Dinov, Ivo D., Heavner, Ben, Tang, Ming, Glusman, Gustavo, Chard, Kyle, Darcy, Mike, Madduri, Ravi, Pa, Judy, Spino, Cathie, Kesselman, Carl, Foster, Ian, Deutsch, Eric W., Price, Nathan D., Van Horn,

Journal:

Year:

2016

Language:

english

File:

PDF, 4.37 MB

english, 2016

5

A wellness study of 108 individuals using personal, dense, dynamic data clouds

Price, Nathan D, Magis, Andrew T, Earls, John C, Glusman, Gustavo, Levy, Roie, Lausted, Christopher, McDonald, Daniel T, Kusebauch, Ulrike, Moss, Christopher L, Zhou, Yong, Qin, Shizhen, Moritz, Rober

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 5.00 MB

english, 2017

6

Comparative analysis of dendritic architecture of identified neurons using the Hausdorff distance metric

Adi Mizrahi, Eyal Ben-Ner, Matthew J. Katz, Klara Kedem, J. Gustavo Glusman, Frederic Libersat

Journal:

The Journal of Comparative Neurology

Year:

2000

Language:

english

File:

PDF, 581 KB

english, 2000

7

Genomic complexity of the variable region-containing chitin-binding proteins in amphioxus

Larry J Dishaw, M Gail Mueller, Natasha Gwatney, John P Cannon, Robert N Haire, Ronda T Litman, Chris T Amemiya, Tatsuya Ota, Lee Rowen, Gustavo Glusman, Gary W Litman

Journal:

Year:

2008

Language:

english

File:

PDF, 1.70 MB

english, 2008

8

KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells

Wei Lu, Daixing Zhou, Gustavo Glusman, Angelita G. Utleg, James T. White, Peter S. Nelson, Thomas J. Vasicek, Leroy Hood, Biaoyang Lin

Journal:

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

9

Self replication and chemical selection in primordial mutually catalytic sets

Doron Lancet, Gustavo Glusman, Daniel Segré, Ora Kedem, Yizhaq Pilpel

Journal:

Origins of Life and Evolution of Biospheres

Year:

1996

Language:

english

File:

PDF, 121 KB

english, 1996

10

The olfactory receptor gene superfamily: data mining, classification, and nomenclature

Gustavo Glusman, Anita Bahar, Dror Sharon, Yitzhak Pilpel, Julia White, Doron Lancet

Journal:

Mammalian Genome

Year:

2000

Language:

english

File:

PDF, 2.23 MB

english, 2000

11

Parasitoid wasp affects metabolism of cockroach host to favor food preservation for its offspring

Gal Haspel, Eran Gefen, Amos Ar, J. Gustavo Glusman, Frederic Libersat

Journal:

Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology

Year:

2005

Language:

english

File:

PDF, 379 KB

english, 2005

12

The human olfactory subgenome: from sequence to structure and evolution

Tania Fuchs, Gustavo Glusman, Shirley Horn-Saban, Doron Lancet, Yitzhak Pilpel

Journal:

Year:

2001

Language:

english

File:

PDF, 1.81 MB

english, 2001

13

Host-Handling Behavior: An Innate Component of Foraging Behavior in the Parasitoid Wasp Ampulex compressa

Tamar Keasar, Noa Sheffer, Gustavo Glusman, Frederic Libersat

Journal:

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

14

Genome Dynamics, Evolution, and Protein Modeling in the Olfactory Receptor Gene Superfamily

DROR SHARON, GUSTAVO GLUSMAN, YITZHAK PILPEL, SHIRLEY HORN-SABARN, DORON LANCET

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 2.34 MB

1998

15

10.1038/79095

Bach, Gideon, Bargal, Ruth, Avidan, Nili, Ben-Asher, Edna, Olender, Zvia, Zeigler, Marcia, Frumkin, Ayala, Raas-Rothschild, Annick, Glusman, Gustavo, Lancet, Doron

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 434 KB

english, 2000

16

Chromosomal Haplotypes by Genetic Phasing of Human Families

Jared C. Roach, Gustavo Glusman, Robert Hubley, Stephen Z. Montsaroff, Alisha K. Holloway, Denise E. Mauldin, Deepak Srivastava, Vidu Garg, Katherine S. Pollard, David J. Galas, Leroy Hood, Arian F.A.

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

17

Position-specific codon conservation in hypervariable gene families

Silvestro G Conticello, Yitzhak Pilpel, Gustavo Glusman, Mike Fainzilber

Journal:

Trends in Genetics

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

18

An enigmatic fourth runt domain gene in the fugu genome: ancestral gene loss versus accelerated evolution

Gustavo Glusman, Amardeep Kaur, Leroy Hood, Lee Rowen

Journal:

BMC Evolutionary Biology

Year:

2004

Language:

english

File:

PDF, 461 KB

english, 2004

19

Low-pass sequencing for microbial comparative genomics

Ah Young Goo, Jared Roach, Gustavo Glusman, Nitin S Baliga, Kerry Deutsch, Min Pan, Sean Kennedy, Shiladitya DasSarma, Wailap Victor Ng, Leroy Hood

Journal:

Year:

2004

Language:

english

File:

PDF, 669 KB

english, 2004

20

Sequence Analysis in the Olfactory Receptor Gene Cluster on Human Chromosome 17: Recombinatorial Events Affecting Receptor Diversity

Gustavo Glusman, Sandy Clifton, Bruce Roe, Doron Lancet

Journal:

Year:

1996

Language:

english

File:

PDF, 308 KB

english, 1996

21

Organization and Evolution of Olfactory Receptor Genes on Human Chromosome 11

Jill A. Buettner, Gustavo Glusman, Nissim Ben-Arie, Purita Ramos, Doron Lancet, Glen A. Evans

Journal:

Year:

1998

Language:

english

File:

PDF, 905 KB

english, 1998

22

Primate Evolution of an Olfactory Receptor Cluster: Diversification by Gene Conversion and Recent Emergence of Pseudogenes

Dror Sharon, Gustavo Glusman, Yitzhak Pilpel, Miriam Khen, Frank Gruetzner, Thomas Haaf, Doron Lancet

Journal:

Year:

1999

Language:

english

File:

PDF, 254 KB

english, 1999

23

Sequence, Structure, and Evolution of a Complete Human Olfactory Receptor Gene Cluster

Gustavo Glusman, Alona Sosinsky, Edna Ben-Asher, Nili Avidan, Dina Sonkin, Anita Bahar, André Rosenthal, Sandra Clifton, Bruce Roe, Concepción Ferraz, Jacques Demaille, Doron Lancet

Journal:

Year:

2000

Language:

english

File:

PDF, 766 KB

english, 2000

24

The Genomic Structure of Human Olfactory Receptor Genes

Alona Sosinsky, Gustavo Glusman, Doron Lancet

Journal:

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

25

Leishmania donovani: Characterization of a 38-kDa membrane protein that cross-reacts with the mammalian G-protein transducin

Dan Cassel, Sigalit Shoubi, Gustavo Glusman, Edna Cukierman, Miriam Rotman, Dan Zilberstein

Journal:

Experimental Parasitology

Year:

1991

Language:

english

File:

PDF, 736 KB

english, 1991

26

Identification and characterization of coding single-nucleotide polymorphisms within a human olfactory receptor gene cluster

Dror Sharon, Yoav Gilad, Gustavo Glusman, Miriam Khen, Doron Lancet, Francis Kalush

Journal:

Year:

2000

Language:

english

File:

PDF, 562 KB

english, 2000

27

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

Ditsa Levanon, Gustavo Glusman, Thorsten Bangsow, Edna Ben-Asher, Dean A Male, Nili Avidan, Carmen Bangsow, Masahira Hattori, Todd D Taylor, Stefan Taudien, Karin Blechschmidt, Nobuyoshi Shimizu, Andr

Journal:

Year:

2001

Language:

english

File:

PDF, 556 KB

english, 2001

28

The RUNX3 gene – sequence, structure and regulated expression

Carmen Bangsow, Nir Rubins, Gustavo Glusman, Yael Bernstein, Varda Negreanu, Dalia Goldenberg, Joseph Lotem, Edna Ben-Asher, Doron Lancet, Ditsa Levanon, Yoram Groner

Journal:

Year:

2001

Language:

english

File:

PDF, 548 KB

english, 2001

29

Comparative Genomics of the Human and Mouse T Cell Receptor Loci

Gustavo Glusman, Lee Rowen, Inyoul Lee, Cecilie Boysen, Jared C. Roach, Arian F.A. Smit, Kai Wang, Ben F. Koop, Leroy Hood

Journal:

Year:

2001

Language:

english

File:

PDF, 735 KB

english, 2001

30

Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3

Ditsa Levanon, Gustavo Glusman, David Bettoun, Edna Ben-Asher, Varda Negreanu, Yael Bernstein, Catherine Harris-Cerruti, Ori Brenner, Raya Eilam, Joseph Lotem, Ofer Fainaru, Dalia Goldenberg, Amir Poz

Journal:

Blood Cells, Molecules, and Diseases

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

31

Genetic Mapping at 3-Kilobase Resolution Reveals Inositol 1,4,5-Triphosphate Receptor 3 as a Risk Factor for Type 1 Diabetes in Sweden

Jared C. Roach, Kerry Deutsch, Sarah Li, Andrew F. Siegel, Lynn M. Bekris, Derek C. Einhaus, Colleen M. Sheridan, Gustavo Glusman, Leroy Hood, Åke Lernmark, Marta Janer

Journal:

The American Journal of Human Genetics

Year:

2006

Language:

english

File:

PDF, 487 KB

english, 2006

32

[IEEE 2009 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - Minneapolis, MN, USA (2009.05.17-2009.05.21)] 2009 IEEE International Workshop on Genomic Signal Processing and Statistics - Enhancing gene detection with computer generated intergenic regions

Caballero, Juan, Glusman, Gustavo

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

33

Clinical applications of sequencing take center stage

Glusman, Gustavo

Journal:

Year:

2013

Language:

english

File:

PDF, 92 KB

english, 2013

34

[IEEE 2009 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - Minneapolis, MN, USA (2009.05.17-2009.05.21)] 2009 IEEE International Workshop on Genomic Signal Processing and Statistics - Mining “junk” DNA to find hidden transcriptional gems

Glusman, Gustavo

Year:

2009

Language:

english

File:

PDF, 481 KB

english, 2009

35

Whole-genome haplotyping approaches and genomic medicine

Glusman, Gustavo, Cox, Hannah C, Roach, Jared C

Journal:

Genome Medicine

Year:

2014

Language:

english

File:

PDF, 493 KB

english, 2014

36

A Gain-of-Function Mutation in TRPV3 Causes Focal Palmoplantar Keratoderma in a Chinese Family

He, Yuqing, Zeng, Kang, Zhang, Xibao, Chen, Qiaolin, Wu, Jiang, Li, Hong, Zhou, Yong, Glusman, Gustavo, Roach, Jared, Etheridge, Alton, Qing, Shizhen, Tian, Qiang, Lee, Inyoul, Tian, Xin, Wang, Xiaoni

Journal:

The Journal of Investigative Dermatology

Year:

2015

Language:

english

File:

PDF, 848 KB

english, 2015

37

Diffuse angiopathy in Adams-Oliver syndrome associated with truncating DOCK6 mutations

Lehman, Anna, Stittrich, Anna-Barbara, Glusman, Gustavo, Zong, Zheyuan, Li, Hong, Eydoux, Patrice, Senger, Christof, Lyons, Christopher, Roach, Jared C., Patel, Millan

Journal:

American Journal of Medical Genetics Part A

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

38

Rare variants in neuronal excitability genes influence risk for bipolar disorder

Ament, Seth A., Szelinger, Szabolcs, Glusman, Gustavo, Ashworth, Justin, Hou, Liping, Akula, Nirmala, Shekhtman, Tatyana, Badner, Judith A., Brunkow, Mary E., Mauldin, Denise E., Stittrich, Anna-Barba

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 890 KB

english, 2015

39

Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease

Krishna, Abhimanyu, Biryukov, Maria, Trefois, Christophe, Antony, Paul MA, Hussong, Rene, Lin, Jake, Heinäniemi, Merja, Glusman, Gustavo, Köglsberger, Sandra, Boyd, Olga, van den Berg, Bart HJ, Linke,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

40

A Third Approach to Gene Prediction Suggests Thousands of Additional Human Transcribed Regions

Glusman, Gustavo, Qin, Shizhen, El-Gewely, M. Raafat, Siegel, Andrew F., Roach, Jared C., Hood, Leroy, Smit, Arian F. A.

Journal:

PLoS Computational Biology

Year:

2006

Language:

english

File:

PDF, 717 KB

english, 2006

41

Identification of copy number variants in whole-genome data using Reference Coverage Profiles

Glusman, Gustavo, Severson, Alissa, Dhankani, Varsha, Robinson, Max, Farrah, Terry, Mauldin, Denise E., Stittrich, Anna B., Ament, Seth A., Roach, Jared C., Brunkow, Mary E., Bodian, Dale L., Vockley,

Journal:

Frontiers in Genetics

Year:

2015

Language:

english

File:

PDF, 5.14 MB

english, 2015

42

Relationship Estimation from Whole-Genome Sequence Data

Li, Hong, Glusman, Gustavo, Hu, Hao, Shankaracharya,, Caballero, Juan, Hubley, Robert, Witherspoon, David, Guthery, Stephen L., Mauldin, Denise E., Jorde, Lynn B., Hood, Leroy, Roach, Jared C., Huff,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

43

Big Biomedical data as the key resource for discovery science

Toga, Arthur W, Foster, Ian, Kesselman, Carl, Madduri, Ravi, Chard, Kyle, Deutsch, Eric W, Price, Nathan D, Glusman, Gustavo, Heavner, Benjamin D, Dinov, Ivo D, Ames, Joseph, Van Horn, John, Kramer, R

Journal:

Journal of the American Medical Informatics Association

Year:

2015

Language:

english

File:

PDF, 774 KB

english, 2015

44

Realistic artificial DNA sequences as negative controls for computational genomics

Caballero, Juan, Smit, Arian F. A., Hood, Leroy, Glusman, Gustavo

Journal:

Nucleic Acids Research

Year:

2014

File:

PDF, 585 KB

2014

45

Realistic artificial DNA sequences as negative controls for computational genomics

Caballero, Juan, Smit, Arian F. A., Hood, Leroy, Glusman, Gustavo

Journal:

Nucleic Acids Research

Year:

2014

Language:

english

File:

PDF, 585 KB

english, 2014

46

Parent-of-origin-specific signatures of de novo mutations

Goldmann, Jakob M, Wong, Wendy S W, Pinelli, Michele, Farrah, Terry, Bodian, Dale, Stittrich, Anna B, Glusman, Gustavo, Vissers, Lisenka E L M, Hoischen, Alexander, Roach, Jared C, Vockley, Joseph G,

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 681 KB

english, 2016

47

Identification of Blood Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics in Acetaminophen and Carbon tetrachloride treated Mouse Models and Acetaminophen Overdose Patients

Qin, Shizhen, Zhou, Yong, Gray, Li, Kusebauch, Ulrike, McEvoy, Laurence, Antoine, Daniel J, Hampson, Lucy, Park, Brian Kevin, Campbell, David S, Caballero, Juan, Glusman, Gustavo, Yan, Xiaowei, Kim, T

Journal:

Journal of Proteome Research

Year:

2016

Language:

english

File:

PDF, 2.33 MB

english, 2016

48

A Data-Rich Longitudinal Wellness Study for the Digital Age: Fixing a Broken Medical System Requires Data About Each Patient

Glusman, Gustavo

Journal:

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

49

Taking Systems Medicine to Heart

Trachana, Kalliopi, Bargaje, Rhishikesh, Glusman, Gustavo, Price, Nathan D., Huang, Sui, Hood, Leroy E.

Journal:

Circulation Research

Year:

2018

Language:

english

File:

PDF, 2.21 MB

english, 2018

50

Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework

Glusman, Gustavo, Rose, Peter W., Prlić, Andreas, Dougherty, Jennifer, Duarte, José M., Hoffman, Andrew S., Barton, Geoffrey J., Bendixen, Emøke, Bergquist, Timothy, Bock, Christian, Brunk, Elizabeth,

Journal:

Genome Medicine

Year:

2017

Language:

english

File:

PDF, 456 KB

english, 2017

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